NewResearch Grade
KPV 50mg
Anti-inflammatory tripeptide & gut repair
KPV (Lys-Pro-Val) is a C-terminal tripeptide fragment of alpha-melanocyte-stimulating hormone (α-MSH). It exerts potent anti-inflammatory effects independently of the melanocortin receptor pathway, acting directly on immune cells to suppress NF-κB signalling. Extensively studied for inflammatory bowel disease, wound healing, and skin inflammation.
- ✓Potent NF-κB inhibition & anti-inflammatory action
- ✓Studied for IBD, Crohn's & colitis models
- ✓Promotes wound healing & skin repair
- ✓Acts independently of melanocortin receptors
- ✓≥99% purity — HPLC verified
Mechanism of Action
KPV is a C-terminal tripeptide fragment of α-MSH (α-melanocyte-stimulating hormone). It exerts potent anti-inflammatory effects by inhibiting NF-κB signalling and reducing pro-inflammatory cytokine production (TNF-α, IL-1β, IL-6). Research focuses on its role in gut inflammation, wound healing, and innate immune modulation.
For research and educational purposes only. This information is derived from published preclinical and clinical literature and does not constitute medical advice.