NewResearch Grade
5-Amino-1MQ 10mg
NAD+ pathway & metabolic enhancement
5-Amino-1MQ is a small molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme that regulates NAD+ metabolism and energy expenditure. By inhibiting NNMT, it raises intracellular NAD+ levels, activates AMPK, and promotes fat cell differentiation reversal — making it a compelling compound in metabolic and longevity research.
- ✓Inhibits NNMT to raise intracellular NAD+
- ✓Activates AMPK for metabolic regulation
- ✓Studied for fat cell differentiation & obesity
- ✓Supports mitochondrial function & energy
- ✓≥99% purity — HPLC verified
Mechanism of Action
5-Amino-1MQ is a small-molecule NNMT (nicotinamide N-methyltransferase) inhibitor. NNMT consumes SAM (S-adenosylmethionine) to methylate nicotinamide, diverting it from NAD+ biosynthesis. By inhibiting NNMT, 5-Amino-1MQ raises intracellular NAD+ and SAM levels, activating SIRT1 and promoting fat cell shrinkage. Research focuses on its role in obesity, metabolic syndrome, and cellular energy regulation.
For research and educational purposes only. This information is derived from published preclinical and clinical literature and does not constitute medical advice.